Author: Cho, Yong-il; Yoon, Kyoung-Jin
Title: An overview of calf diarrhea - infectious etiology, diagnosis, and intervention Document date: 2014_3_19
ID: uxghqdei_8
Snippet: Bovine viral diarrhea virus is an enveloped, positive-sense, single-stranded RNA virus (12.3 kb) and a An overview of calf diarrhea -infectious etiology, diagnosis, and intervention 3 member of the genus Pestivirus in the family Flaviviridae [40] . There are three species included in the genus: BVDV, border disease virus, and classical swine fever virus. BVDV can be divided into two types (BVDV1 and BVDV2) based on sequence similarity of the 5' u.....
Document: Bovine viral diarrhea virus is an enveloped, positive-sense, single-stranded RNA virus (12.3 kb) and a An overview of calf diarrhea -infectious etiology, diagnosis, and intervention 3 member of the genus Pestivirus in the family Flaviviridae [40] . There are three species included in the genus: BVDV, border disease virus, and classical swine fever virus. BVDV can be divided into two types (BVDV1 and BVDV2) based on sequence similarity of the 5' untranslated region (UTR) in the viral genome. In addition to these two types, BVDV3 was recently proposed as tentative species together with other Pestivirus species (e.g., border disease virus type 2, Pronghorn, and Bungowannah) [46] . Each type can be further divided into two biotypes (cytopathic and noncytopathic) based on their ability to cause lytic cytopathic effects in cell culture. Noncytopathic strains of BVDV are responsible for persistent infection of the virus in cattle [52] . To date, 15 (BVDV1a to BVDV 1o) BVDV1 and two (BVDV2a and BVDV2b) BVDV2 subgenotypes have been recognized [40, 63] . BVDV1a, BVDV1b, and BVDV2a are the most prevalent subgenotypes in US cattle populations [44] . BVDV1c is the most common subgenotype in Australia [118] .
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