Author: Zhang, Fen; Liu, Chang; Wang, Lei; Cao, Xi; Wang, Ying Ying; Yang, Jin Kui
Title: Antioxidant effect of angiotensin (1-7) in the protection of pancreatic ß cell function Document date: 2016_7_13
ID: xndjru4d_20
Snippet: Ang (1-7)-treated INS-1 cells (Fig. 5A) , which was inhibited by treatment with A779. Furthermore, the red fluorescence, which indicates greater MMP, increased significantly following the addition of Ang (1-7), which was blocked by A779 treatment, as demonstrated by a significant increase in green fluorescence (Fig. 5B ). As shown in Fig. 5 , INS-1 cells treated with 250 µmol/l H 2 O 2 for 15 min exhibited a decrease in the level of MMP caused b.....
Document: Ang (1-7)-treated INS-1 cells (Fig. 5A) , which was inhibited by treatment with A779. Furthermore, the red fluorescence, which indicates greater MMP, increased significantly following the addition of Ang (1-7), which was blocked by A779 treatment, as demonstrated by a significant increase in green fluorescence (Fig. 5B ). As shown in Fig. 5 , INS-1 cells treated with 250 µmol/l H 2 O 2 for 15 min exhibited a decrease in the level of MMP caused by CCCP compared with that in the controls at 16.7 mM glucose. Pre-treatment with a 10 -8 mol/l Ang (1-7) for 2 h prior to adding H 2 O 2 increased the level of MMP significantly. Treatment with 10 -8 mol/l A779 for 2 h inhibited this effect.
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