Author: Kang, Soo Jung; Kim, Nam Su
Title: Association of Toll-like receptor 2-positive monocytes with coronary artery lesions and treatment nonresponse in Kawasaki disease Document date: 2017_7_31
ID: tk1bxztw_45
Snippet: Moreover, activation of TLR2 may be an early upstream res ponse preceding the production of proinflammatory cytokines, e.g., TNFα and IL1β, which have been shown to be important in CAL pathogenesis 12, 18, 25) . As there may be a time lag between TLR2 acti vation and the subsequent production of proinflammatory cyto kines, monitoring FTLR2% could potentially be used as a relatively early predictor of CAL development, before the eleva tion of se.....
Document: Moreover, activation of TLR2 may be an early upstream res ponse preceding the production of proinflammatory cytokines, e.g., TNFα and IL1β, which have been shown to be important in CAL pathogenesis 12, 18, 25) . As there may be a time lag between TLR2 acti vation and the subsequent production of proinflammatory cyto kines, monitoring FTLR2% could potentially be used as a relatively early predictor of CAL development, before the eleva tion of serum cytokine levels becomes clinically apparent.
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