Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_203
Snippet: Results: MCT1 is expressed at higher levels relative to MCT4 in canine osteosarcoma cell lines. Small molecule inhibitors directed against MCT1/4 do not significantly decrease cell proliferation. Synergistic activity was observed when cells were treated with doxorubicin or metformin in the presence of MCT1 and MCT4 small molecule inhibitors......
Document: Results: MCT1 is expressed at higher levels relative to MCT4 in canine osteosarcoma cell lines. Small molecule inhibitors directed against MCT1/4 do not significantly decrease cell proliferation. Synergistic activity was observed when cells were treated with doxorubicin or metformin in the presence of MCT1 and MCT4 small molecule inhibitors.
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