Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_211
Snippet: The aim of this study was to document the receptor expression in feline somatotrophinomas and to compare this to the healthy feline pituitary. We utilised a novel customised multiplex RT-qPCR assay to investigate the expression profile of the somatostatin and dopamine receptors in GH-secreting pituitary adenomas. Pituitary adenoma RNA was extracted from 20 GH-secreting adenomas and eight control cats followed by multiplex RT-qPCR analyses for mul.....
Document: The aim of this study was to document the receptor expression in feline somatotrophinomas and to compare this to the healthy feline pituitary. We utilised a novel customised multiplex RT-qPCR assay to investigate the expression profile of the somatostatin and dopamine receptors in GH-secreting pituitary adenomas. Pituitary adenoma RNA was extracted from 20 GH-secreting adenomas and eight control cats followed by multiplex RT-qPCR analyses for multiple genes, including somatostatin receptors (SSTR1-5), dopamine receptor (D2R), growth hormone receptor, growth hormone secretagogue receptor and the housekeeper RPL18.
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