Author: Kang, Soo Jung; Kim, Nam Su
Title: Association of Toll-like receptor 2-positive monocytes with coronary artery lesions and treatment nonresponse in Kawasaki disease Document date: 2017_7_31
ID: tk1bxztw_5
Snippet: Activation of TLR2 can trigger production of IL10, an antiin flammatory as well as a proinflammatory cytokine with regulatory properties, which is involved in the inhibition of monocyte and macrophage replication 19) . However, increased serum level of IL 10 (sIL10) in patients with KD has been correlated with CAL de velopment in the acute stage of the disease, and it is also con sidered an indicator of IVIG resistance 20, 21) . To date, the role.....
Document: Activation of TLR2 can trigger production of IL10, an antiin flammatory as well as a proinflammatory cytokine with regulatory properties, which is involved in the inhibition of monocyte and macrophage replication 19) . However, increased serum level of IL 10 (sIL10) in patients with KD has been correlated with CAL de velopment in the acute stage of the disease, and it is also con sidered an indicator of IVIG resistance 20, 21) . To date, the role of sIL10 in KD has not been as extensively studied as the role of TNFα, IL1β, or IL6.
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