Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_557
Snippet: GHV-derived DNA was detected in 1.4% (23/1,738) of Japanese domestic cats. BLAST analysis revealed that all of them showed high similarity with FcaGHVs which were isolated from domestic cats in the United States. Phylogenic analysis also revealed that all Japanese isolates formed one cluster with FcaGHV. In the univariable analysis, older age (OR, 4.93; 95% CI, 1.43-16.99; P < 0.01), male (OR, 2.51; 95% CI, 0.98-6.40; P = 0.05), FIV infection (OR.....
Document: GHV-derived DNA was detected in 1.4% (23/1,738) of Japanese domestic cats. BLAST analysis revealed that all of them showed high similarity with FcaGHVs which were isolated from domestic cats in the United States. Phylogenic analysis also revealed that all Japanese isolates formed one cluster with FcaGHV. In the univariable analysis, older age (OR, 4.93; 95% CI, 1.43-16.99; P < 0.01), male (OR, 2.51; 95% CI, 0.98-6.40; P = 0.05), FIV infection (OR, 5.35; 95% CI, 2.30-12.46; P < 0.01), FeLV infection (OR, 2.02; 95% CI, 0.74-5.50; P = 0.18) and sick cat (OR, 2.37; 95% CI, 0.80-7.02; P = 0.12) were statistically selected as risk factors for GHV infection. In the following multivariable analysis, older age (OR, 3.84; 95% CI, 1.06-13.86; P = 0.04) and FIV infection (OR, 4.11; 95% CI, 1.52-11.11; P < 0.01) were found to be significant and independent risk factors for GHV infection.
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