Selected article for: "active infection and syphilis seropositivity"
Author: Wu, Xiaobing; Guan, Yang; Ye, Jianbin; Fu, Hanlin; Zhang, Chunlai; Lan, Lina; Wu, Fengxin; Tang, Fen; Wang, Feng; Cai, Yumao; Yu, Weiye; Feng, Tiejian
Title: Association between syphilis seroprevalence and age among blood donors in Southern China: an observational study from 2014 to 2017
  • Document date: 2019_11_2
    • ID: ubnv0fdw_80
    Snippet: Consistent with the results of some previous studies, the prevalence of both syphilis seropositivity and active infection were higher among females than males. 21, 22 It may stem partly from the different physiology and anatomy of the genital organs between both sexes, leading to females being more likely to contract STDs in receptive vaginal sex behaviours. 31 Some studies have proved that the male-to-female transmission rate is higher than the .....
    Document: Consistent with the results of some previous studies, the prevalence of both syphilis seropositivity and active infection were higher among females than males. 21, 22 It may stem partly from the different physiology and anatomy of the genital organs between both sexes, leading to females being more likely to contract STDs in receptive vaginal sex behaviours. 31 Some studies have proved that the male-to-female transmission rate is higher than the female-to-male rate in certain STDs, such as HIV. 31, 32 Besides, a proportion of females have multiple sex partners during their lifetime. A previous study has found that the syphilis prevalence among husbands of 2261 syphilis-infected pregnant women was < 30%. 33 Premarital or extramarital sexual partners may greatly increase the risk of syphilis infection among females. Additionally, serological response differs between males and females. 34 Females are more likely to be serofast [defined as remaining positive in a non-treponemal test and keeping the titre at a certain level (mostly 1:8 or below) after recommended therapy and follow-up 1 to 3 years according to syphilis stage] when comparing with males, 35 leading to more females staying in the state of active infection. The exact mechanism underlying this difference is unclear, but it may be partly associated with the varied immune system between both sexes. 34 Furthermore, men who have sex with men are considered a major high-risk subgroup for syphilis infection and are permanently deferred from blood donation in

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