Author: William Binning; Aja E. Hogan-Cann; Diana Yae Sakae; Matthew Maksoud; Valeriy Ostapchenko; Mohammed Al-Onaizi; Sara Matovic; Wei-Yang Lu; Marco A. M. Prado; Wataru Inoue; Vania F. Prado
Title: Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice Document date: 2020_1_28
ID: ely200x3_122
Snippet: A) Experimental approach and timeline for CNO treatment, LPS challenge and behavior assessments. CNO (1 mg/kg; i.p.); LPS (0.1 mg/kg; i.p.). B) Body weight decreased after LPS injection (day 4) for both CNO-and vehicle-treated mice (n=11 per treatment, **** in comparison to days 1-4). C) Time spent investigating juvenile mouse in a three-chamber social preference task at 2h and 24h after LPS treatment. D) Locomotor activity in an open field 24h a.....
Document: A) Experimental approach and timeline for CNO treatment, LPS challenge and behavior assessments. CNO (1 mg/kg; i.p.); LPS (0.1 mg/kg; i.p.). B) Body weight decreased after LPS injection (day 4) for both CNO-and vehicle-treated mice (n=11 per treatment, **** in comparison to days 1-4). C) Time spent investigating juvenile mouse in a three-chamber social preference task at 2h and 24h after LPS treatment. D) Locomotor activity in an open field 24h after LPS treatment.
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