Author: Lu, Yan; Jiang, Yun; Ling, Lijun; Zhang, Yunyi; Li, Hong; Chen, Daofeng
Title: Beneficial effects of Houttuynia cordata polysaccharides on “two-hit” acute lung injury and endotoxic fever in rats associated with anti-complementary activities Document date: 2017_12_8
ID: q4r36tpw_57
Snippet: In conclusion, this study demonstrated that CHCP can ameliorate not only the "two-hit" ALI, but also the LPS-induced fever in rats, both of which are associated with inhibition of the excessively activated complement system. The anti-complementary polysaccharides were shown to play an important role in the heat-clearing effect of H. cordata. Moreover, CHCP has no interference with the coagulation system. CHCP could be a promising natural compleme.....
Document: In conclusion, this study demonstrated that CHCP can ameliorate not only the "two-hit" ALI, but also the LPS-induced fever in rats, both of which are associated with inhibition of the excessively activated complement system. The anti-complementary polysaccharides were shown to play an important role in the heat-clearing effect of H. cordata. Moreover, CHCP has no interference with the coagulation system. CHCP could be a promising natural complement inhibitor to be applied in the treatment of complementassociated diseases.
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