Selected article for: "binary order and disorder order"
Author: Rahaman, Jordon; Siltberg-Liberles, Jessica
Title: Avoiding Regions Symptomatic of Conformational and Functional Flexibility to Identify Antiviral Targets in Current and Future Coronaviruses
  • Document date: 2016_11_9
    • ID: pygykil7_27
    Snippet: To compare the disorder-to-order transition rates (DOT) for all protein families where the binary matrices of disorder and order include both states, the quadrant count ratio (QCR) was estimated as a measure of association in assigning slower than average vs. faster than average transition rates. For IUPred 0.4 vs. IUPred 0.5, for IUPred 0.5 vs DISOPRED2, and for IUPred 0.4 vs. DISOPRED2, the QCRs (table 2) . For nucleocapsid and NSP8, the positi.....
    Document: To compare the disorder-to-order transition rates (DOT) for all protein families where the binary matrices of disorder and order include both states, the quadrant count ratio (QCR) was estimated as a measure of association in assigning slower than average vs. faster than average transition rates. For IUPred 0.4 vs. IUPred 0.5, for IUPred 0.5 vs DISOPRED2, and for IUPred 0.4 vs. DISOPRED2, the QCRs (table 2) . For nucleocapsid and NSP8, the positive associations are weaker, suggesting that many sites have IUPred disorder propensity in the 0.4 to 0.5 range and large differences between IUPred and DISOPRED2, in accordance with the large disagreement between the binary assignment of these predictors (tables 1 and 2).

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