Selected article for: "immune response and inflammatory response"

Author: William Binning; Aja E. Hogan-Cann; Diana Yae Sakae; Matthew Maksoud; Valeriy Ostapchenko; Mohammed Al-Onaizi; Sara Matovic; Wei-Yang Lu; Marco A. M. Prado; Wataru Inoue; Vania F. Prado
Title: Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice
  • Document date: 2020_1_28
  • ID: ely200x3_93
    Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10. 1101 /2020 Repetitive peripheral administration of LPS has been shown to induce immune memory in microglia that can then modify their response to inflammatory stimuli (Wendeln et al., 2018) . To test the possibility that repetitive activation of hM3Dq could affect the subsequent microglial responses to LPS, we treated CX3CR1CreER(+/-)-hM3Dq(+/-) mice.....
    Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10. 1101 /2020 Repetitive peripheral administration of LPS has been shown to induce immune memory in microglia that can then modify their response to inflammatory stimuli (Wendeln et al., 2018) . To test the possibility that repetitive activation of hM3Dq could affect the subsequent microglial responses to LPS, we treated CX3CR1CreER(+/-)-hM3Dq(+/-) mice for 4 days with vehicle or CNO

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