Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_789
Snippet: Torsemide was administered intragastrically at a single dose of 6 mg/kg to six healthy adult mares. Blood samples were collected at predetermined time points over a period of 48 hours. Plasma torsemide concentrations were measured by the use of high performance liquid chromatography, and serum biochemical profiles were examined. Student's t-test with Bonferroni correction was used to identify differences in pharmacokinetic and biochemical paramet.....
Document: Torsemide was administered intragastrically at a single dose of 6 mg/kg to six healthy adult mares. Blood samples were collected at predetermined time points over a period of 48 hours. Plasma torsemide concentrations were measured by the use of high performance liquid chromatography, and serum biochemical profiles were examined. Student's t-test with Bonferroni correction was used to identify differences in pharmacokinetic and biochemical parameters between baseline (pre) and 24 hour post drug administration (post). Statistical significance was set at P < 0.05.
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