Clinical and Laboratory Profiles of 75 Hospitalized Patients with Novel Coronavirus Disease 2019 in Hefei, China

Zonghao Zhao; Jiajia Xie; Ming Yin; Yun Yang; Hongliang He; Tengchuan Jin; Wenting Li; Xiaowu Zhu; Jing Xu; Changcheng Zhao; Lei Li; Yi Li; Hylemariam Mihiretie Mengist; Ayesha Zahid; Ziqin Yao; Chengchao Ding; Yingjie Qi; Yong Gao; Xiaoling Ma

The copyright holder for this preprint . https: //doi.org/10.1101 //doi.org/10. /2020 CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. 114 We also examined other respiratory viruses, including influenza, avian influenza, 115 respiratory syncytial virus, adenovirus, parainfluenza virus, SARS-CoV and 116 MERS-CoV, with realtime RT-PCR. Hematological parameters including blood 117 routine, blood biochemistry, coagulation profile, and infection-related biomarkers 118 were recorded. Plasma cytokine interleukin 6 (IL-6) levels were detected by ELISA. 119 And the CD4 + and CD8 + T cell subsets were counted using flow cytometry. 120 Statistical analysis 121 We presented continuous measurements as median (IQR) and categorical variables 122 as number (%). Continuous variables were analyzed using the Mann-Whitney test. 123 For laboratory results, we also assessed whether the measurements were outside the 124 normal range. Graphpad prism 8.3 was used for all analyses. A two-sided α of less 125 than 0.05 was considered statistically significant.