Author: Xing, Liang; Sun, Feng; Wang, Zhendong; Li, Yan; Yang, Zhifang; Wang, Fengshan; Zhai, Guangxi; Tan, Haining
Title: Characterization and bioactivity of self-assembled anti-angiogenic chondroitin sulfate-ES2-AF nanoparticle conjugate Document date: 2019_4_10
ID: x8f598x2_36
Snippet: In general, a K d value in the range of 10 -5 -10 -12 indicates a strong sample-to-ligand affinity. 43 According to the results presented here, the affinity of the polypeptide ES2-AF to the CD44 receptor was weak, and CS, a ligand of the CD44 receptor, can bind specifically to the CD44 receptor. Therefore, the affinity of CS to CD44 receptors was theoretically stronger than the unmodified ES2-AF, and it could be concluded that CS could increase t.....
Document: In general, a K d value in the range of 10 -5 -10 -12 indicates a strong sample-to-ligand affinity. 43 According to the results presented here, the affinity of the polypeptide ES2-AF to the CD44 receptor was weak, and CS, a ligand of the CD44 receptor, can bind specifically to the CD44 receptor. Therefore, the affinity of CS to CD44 receptors was theoretically stronger than the unmodified ES2-AF, and it could be concluded that CS could increase the targeting of drugs to tumor tissues.
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