Selected article for: "aspartate aminotransferase and AST aspartate aminotransferase"
Author: Choi, Won Suk; Kang, Cheol-In; Kim, Yonjae; Choi, Jae-Phil; Joh, Joon Sung; Shin, Hyoung-Shik; Kim, Gayeon; Peck, Kyong Ran; Chung, Doo Ryeon; Kim, Hye Ok; Song, Sook Hee; Kim, Yang Ree; Sohn, Kyung Mok; Jung, Younghee; Bang, Ji Hwan; Kim, Nam Joong; Lee, Kkot Sil; Jeong, Hye Won; Rhee, Ji-Young; Kim, Eu Suk; Woo, Heungjeong; Oh, Won Sup; Huh, Kyungmin; Lee, Young Hyun; Song, Joon Young; Lee, Jacob; Lee, Chang-Seop; Kim, Baek-Nam; Choi, Young Hwa; Jeong, Su Jin; Lee, Jin-Soo; Yoon, Ji Hyun; Wi, Yu Mi; Joung, Mi Kyong; Park, Seong Yeon; Lee, Sun Hee; Jung, Sook-In; Kim, Shin-Woo; Lee, Jae Hoon; Lee, Hyuck; Ki, Hyun Kyun; Kim, Yeon-Sook
Title: Clinical Presentation and Outcomes of Middle East Respiratory Syndrome in the Republic of Korea
  • Document date: 2016_6_30
    • ID: pztrwvib_14
    Snippet: One hundred fifty-two patients (81.7%) manifested fever and more than 50% had developed cough at admission. Almost all of the patients (95.2%) developed fever during the course of disease. Unstable vital signs were observed in approximately a quarter of the patients at admission. Compared with survivors, the deceased more frequently presented with dyspnea, hypotension, and tachypnea at admission. At admission, 178 (95.7%) of the 186 patients unde.....
    Document: One hundred fifty-two patients (81.7%) manifested fever and more than 50% had developed cough at admission. Almost all of the patients (95.2%) developed fever during the course of disease. Unstable vital signs were observed in approximately a quarter of the patients at admission. Compared with survivors, the deceased more frequently presented with dyspnea, hypotension, and tachypnea at admission. At admission, 178 (95.7%) of the 186 patients underwent one or more blood tests (Table 1) including complete blood counts in 178 (95.7%), C-reactive protein (CRP) analyses in 168 (90.3%), and liver function and blood chemistry tests in 173 (93.0%). Among those, 42.1% had leukopenia (<4,000 cells/mm 3 ), 4.5% had leukocytosis (>10,000/mm 3 ), 32.0% had anemia (<12 g/dL), and 46.6% had thrombocytopenia (<150,000 /mm 3 ). CRP was elevated (>3 mg/dL) in 47.6% of patients. Elevated level of aspartate aminotransferase (AST) was observed in 43.4%, whereas elevated creatinine was observed in only 5.8% of patients. Among the 103 patients who underwent urinalysis, 44(42.7%) had proteinuria and 36(35.0%) had hematuria. Forty-four patients underwent arterial blood gas analysis, which revealed a decreased PaO 2 :FiO 2 ratio (<300) in 56.8% of patients. Compared with survivors, the deceased more frequently exhibited leucocytosis, hypoalbuminaemia, elevated serum creatinine and CRP levels, and hypoxemia (PaO2:FiO2 ratio <300).

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