Author: Rose, Rebecca; Constantinides, Bede; Tapinos, Avraam; Robertson, David L; Prosperi, Mattia
Title: Challenges in the analysis of viral metagenomes Document date: 2016_8_3
ID: x3u9i1vq_1
Snippet: In the last decade, at least seven separate viral outbreaks have caused tens of thousands of human deaths (Woolhouse, Rambaut, and Kellam, 2015) , and the ever-increasing density of livestock, rate of habitat destruction, and extent of human global travel provides a fertile environment for new pandemics to emerge from host switching events (Delwart 2007; Fancello, Raoult, and Desnues 2012) , as was the case for SARS, Ebola, Middle East Respirator.....
Document: In the last decade, at least seven separate viral outbreaks have caused tens of thousands of human deaths (Woolhouse, Rambaut, and Kellam, 2015) , and the ever-increasing density of livestock, rate of habitat destruction, and extent of human global travel provides a fertile environment for new pandemics to emerge from host switching events (Delwart 2007; Fancello, Raoult, and Desnues 2012) , as was the case for SARS, Ebola, Middle East Respiratory Syndrome (MERS), and influenza-A (H1N1) (Castillo-Chavez et al. 2015) . At present we have a limited grasp of the extent of viral diversity present in the environment: the 2014 database release from the International Committee for the Taxonomy of Viruses classified just 7 orders, 104 families, 505 genera, and 3286 species (http://www.ictvon line.org/virustaxonomy.asp); yet, one study estimated that there are at least 320,000 virus species infecting mammals alone (Anthony et al. 2013 ).
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