Author: Xing, Liang; Sun, Feng; Wang, Zhendong; Li, Yan; Yang, Zhifang; Wang, Fengshan; Zhai, Guangxi; Tan, Haining
Title: Characterization and bioactivity of self-assembled anti-angiogenic chondroitin sulfate-ES2-AF nanoparticle conjugate Document date: 2019_4_10
ID: x8f598x2_26
Snippet: The tube formation assay was used to investigate the effects of ES2-AF, CS-ES2-AF, and CS&ES2-AF on blood vessel formation in EA.hy926 cells. 23, 24 The number of tubes is represented by the number of branches/fields. Different concentrations of the drugs were added to 48-well plates and incubated for 8 hours. The plates were photographed under a fluorescence microscope ( Figure 4B ); the tube formation of the endothelial cells could be observed .....
Document: The tube formation assay was used to investigate the effects of ES2-AF, CS-ES2-AF, and CS&ES2-AF on blood vessel formation in EA.hy926 cells. 23, 24 The number of tubes is represented by the number of branches/fields. Different concentrations of the drugs were added to 48-well plates and incubated for 8 hours. The plates were photographed under a fluorescence microscope ( Figure 4B ); the tube formation of the endothelial cells could be observed from the figure. A large number of tubes were formed in the control group after incubation for 8 hours. Compared with the control group, the number of tubes formed in the lowconcentration experimental group was less, indicating that the low concentration of the drug could also inhibit the endothelial cell tube formation. When the concentration was increased to 200 μg/mL, the number of tube branches/field in the CS-ES2-AF group was significantly reduced, and most cells were isolated, while more tube branches/field were still visible in the ES2-AF group.
Search related documents:
Co phrase search for related documents- blood vessel and cell tube: 1
- blood vessel and cell tube formation: 1
- blood vessel and control group: 1, 2, 3, 4, 5, 6, 7, 8
- blood vessel and CS group: 1
- blood vessel and endothelial cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- blood vessel formation and cell blood vessel formation: 1, 2
- blood vessel formation and endothelial cell: 1
- cell tube and control group: 1, 2
- cell tube and CS group: 1
- cell tube and endothelial cell: 1, 2, 3, 4, 5, 6
- cell tube and endothelial cell tube formation: 1, 2, 3, 4
- cell tube formation and control group: 1, 2
- cell tube formation and CS group: 1
- cell tube formation and endothelial cell: 1, 2, 3, 4, 5, 6, 7
- cell tube formation and endothelial cell tube formation: 1, 2, 3, 4, 5
- control group and different concentration: 1, 2
- control group and endothelial cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- control group and endothelial cell tube formation: 1
- control group and experimental group: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
Co phrase search for related documents, hyperlinks ordered by date