Author: Farhadi, Tayebeh; Hashemian, Seyed MohammadReza
Title: Computer-aided design of amino acid-based therapeutics: a review Document date: 2018_5_14
ID: q69f57el_12
Snippet: The problem of predicting the fold of an unknown sequence could be solved by utilizing templates. Since the fold is unaltered, the backbone atoms are directly located on this framework. 3 Moreover, to generate a functional protein, the side chains that can effectively stabilize the structure are added to the backbone. 37, 38 Routine concerns and methods for template-based protein design are reviewed below......
Document: The problem of predicting the fold of an unknown sequence could be solved by utilizing templates. Since the fold is unaltered, the backbone atoms are directly located on this framework. 3 Moreover, to generate a functional protein, the side chains that can effectively stabilize the structure are added to the backbone. 37, 38 Routine concerns and methods for template-based protein design are reviewed below.
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