Clinical and laboratory profiles of hospitalized children with acute respiratory virus infection

Choi, Eunjin; Ha, Kee-Soo; Song, Dae Jin; Lee, Jung Hwa; Lee, Kwang Chul

There were no differences in comorbidities such as premature birth, congenital heart disease and chronic lung disease among viral ARI cases. RSV A, RSV B, and hMPV were more associated with lower ARI compared with other viruses. Croup was most commonly associated with PIV and hCV (20.5%, 31.0%), while pneumonia was associated with RSV A, RSV B, and hMPV (63.0%, 52.1%, and 68.5%). Additionally, bronchiolitis was associated with RSV A and B (24.6% and 29.9%), while asthma exacerbations were associated with hRV (8.0%, P<0.001) only. Most cases of ARI presented with cough and rhinorrhea (data not shown). While fever was associated with many viruses, RSV A, RSV B, and hRV were not significantly associated with fever (41.4%, 26.5%, and 28.8%, P<0.05). AdV and PIV were associated with fever lasting more than 7 days (15.2%, Headache was significantly associated with hEV and AdV (16.8% and 6.2%, P<0.05). Antibiotics were used more frequently in cases with AdV and hMPV (75.7% and 83.1%, P<0.05), and steroids were used more frequently in cases with hRV (8.6%, P<0.001). RSV was associated with greater nebulizer use, O 2 supplementation and intensive care unit care, and it was also associated with a longer hospital stay ( Table 2 ).