Selected article for: "antiviral therapy and combination therapy"
Author: Choi, Won Suk; Kang, Cheol-In; Kim, Yonjae; Choi, Jae-Phil; Joh, Joon Sung; Shin, Hyoung-Shik; Kim, Gayeon; Peck, Kyong Ran; Chung, Doo Ryeon; Kim, Hye Ok; Song, Sook Hee; Kim, Yang Ree; Sohn, Kyung Mok; Jung, Younghee; Bang, Ji Hwan; Kim, Nam Joong; Lee, Kkot Sil; Jeong, Hye Won; Rhee, Ji-Young; Kim, Eu Suk; Woo, Heungjeong; Oh, Won Sup; Huh, Kyungmin; Lee, Young Hyun; Song, Joon Young; Lee, Jacob; Lee, Chang-Seop; Kim, Baek-Nam; Choi, Young Hwa; Jeong, Su Jin; Lee, Jin-Soo; Yoon, Ji Hyun; Wi, Yu Mi; Joung, Mi Kyong; Park, Seong Yeon; Lee, Sun Hee; Jung, Sook-In; Kim, Shin-Woo; Lee, Jae Hoon; Lee, Hyuck; Ki, Hyun Kyun; Kim, Yeon-Sook
Title: Clinical Presentation and Outcomes of Middle East Respiratory Syndrome in the Republic of Korea
  • Document date: 2016_6_30
    • ID: pztrwvib_28
    Snippet: The case fatality rate observed in this study was lower than that reported in other studies of previous MERS outbreaks (20.4% vs. 36.5-65%) [4, 5, 10] . This low case fatality rate could be attributed to the application of aggressive treatment measures, including antiviral agents, mechanical ventilation, or ECMO. Antiviral treatments were administered to 74.5% of the patients, although clinical decisions for their use were made by attending physi.....
    Document: The case fatality rate observed in this study was lower than that reported in other studies of previous MERS outbreaks (20.4% vs. 36.5-65%) [4, 5, 10] . This low case fatality rate could be attributed to the application of aggressive treatment measures, including antiviral agents, mechanical ventilation, or ECMO. Antiviral treatments were administered to 74.5% of the patients, although clinical decisions for their use were made by attending physicians. During the MERS-CoV epidemic in the Republic of Korea, the Korean Society of Infectious Diseases and the Korean Society for Chemotherapy collaborated to generate and distribute recommendations for the use of antiviral treatments based on existing available data from experiences with SARS and MERS [12, 13] . We were not able to assess the clinical impact of antiviral therapy on outcomes, as most patients with severe pneumonia received combination antiviral therapy along with comprehensive supportive care. The therapeutic efficacy of combination antiviral therapy should be evaluated in further studies.

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