Author: Al-Mulla, Hawaa M. N.; Turrell, Lauren; Smith, Nicola M.; Payne, Luke; Baliji, Surendranath; Züst, Roland; Thiel, Volker; Baker, Susan C.; Siddell, Stuart G.; Neuman, Benjamin W.
Title: Competitive Fitness in Coronaviruses Is Not Correlated with Size or Number of Double-Membrane Vesicles under Reduced-Temperature Growth Conditions Document date: 2014_4_1
ID: tfuupgkg_11
Snippet: Clusters of DMVs were observed next to regions of CM in 17Cl-1 cells infected with wild-type and mutant viruses (Fig. 3A) . However, all of the mutants produced smaller DMVs than wildtype virus, varying from nearly wild-type size (Brts105) to approximately 10% smaller (Brts31, Wüts18, and Albts22) to 17% smaller (Albts16). Many DMV-containing cells also contained intracellular virus particles (Fig. 3B) , which did not differ significantly in siz.....
Document: Clusters of DMVs were observed next to regions of CM in 17Cl-1 cells infected with wild-type and mutant viruses (Fig. 3A) . However, all of the mutants produced smaller DMVs than wildtype virus, varying from nearly wild-type size (Brts105) to approximately 10% smaller (Brts31, Wüts18, and Albts22) to 17% smaller (Albts16). Many DMV-containing cells also contained intracellular virus particles (Fig. 3B) , which did not differ significantly in size from wild-type controls.
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