Author: Borges, Marcos Carvalho; Castro, Luiza Antunes; da Fonseca, Benedito Antonio Lopes
Title: Chloroquine use improves dengue-related symptoms Document date: 2013_8_23
ID: s8tq6d68_16
Snippet: Chloroquine is a 9-aminoquinoline known since 1934 that has a long history of use as an antimalarial agent and as an alternative drug to treat a variety of chronic diseases (Savarino et al. 2003 , Tutor-Ureta & Yebra-Bango 2005 . The rationales for using chloroquine in dengue patients include the drug's anti-inflammatory property, possible antiviral effect, with action on flaviviruses, low cost, universal availability and safety and global public.....
Document: Chloroquine is a 9-aminoquinoline known since 1934 that has a long history of use as an antimalarial agent and as an alternative drug to treat a variety of chronic diseases (Savarino et al. 2003 , Tutor-Ureta & Yebra-Bango 2005 . The rationales for using chloroquine in dengue patients include the drug's anti-inflammatory property, possible antiviral effect, with action on flaviviruses, low cost, universal availability and safety and global public health importance of dengue. Recently, a potential use of chloroquine has been described in some viral infections, such as influenza, human immunodeficiency virus and severe acute respiratory syndrome (coronavirus) (Lanciotti et al. 1992 , Savarino et al. 2003 , Vincent et al. 2005 , Adachi et al. 2007 , Di Trani et al. 2007 , Keyaerts et al. 2009 , Martinson et al. 2010 .
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