Selected article for: "antibody library and library size"
Author: Feng, Mingqian; Bian, Hejiao; Wu, Xiaolin; Fu, Tianyun; Fu, Ying; Hong, Jessica; Fleming, Bryan D; Flajnik, Martin F; Ho, Mitchell
Title: Construction and next-generation sequencing analysis of a large phage-displayed V(NAR) single-domain antibody library from six naïve nurse sharks
  • Document date: 2018_11_7
    • ID: wc6k06sm_14
    Snippet: In the present study, we developed the EASeL method to construct phage display libraries based on PCR extension assembly followed by self-ligation. By using this EASeL method, we successfully constructed a large phagedisplayed V NAR library with a size of 10 10 from six antigen-Antibody Therapeutics, 2019 5 We also demonstrated that Type I and Type II shark V NAR binders can be produced from E. coli as functional single-domain proteins. The large.....
    Document: In the present study, we developed the EASeL method to construct phage display libraries based on PCR extension assembly followed by self-ligation. By using this EASeL method, we successfully constructed a large phagedisplayed V NAR library with a size of 10 10 from six antigen-Antibody Therapeutics, 2019 5 We also demonstrated that Type I and Type II shark V NAR binders can be produced from E. coli as functional single-domain proteins. The large nurse shark V NAR singledomain phage library described here provides an attractive single-domain antibody platform for drug discovery.

    Search related documents:
    Co phrase search for related documents
    • antibody platform and drug discovery: 1, 2, 3
    • antibody platform and drug discovery antibody platform: 1, 2
    • antibody platform and EASeL method: 1
    • antibody platform and large nurse: 1
    • antibody platform and large nurse shark: 1
    • antibody platform and PCR extension: 1
    • antibody platform and PCR extension assembly: 1
    • antibody platform and phage library: 1, 2, 3
    • antibody platform and present study: 1
    • antibody platform and self ligation: 1
    • antibody platform and single domain: 1, 2, 3, 4, 5
    • coli produce and drug discovery: 1
    • coli produce and present study: 1
    • display library and drug discovery: 1, 2
    • display library and phage library: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • display library and present study: 1, 2
    • display library and single domain: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • drug discovery and phage library: 1, 2
    • drug discovery and present study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25