Author: Chen, Haifeng; Mammel, Mark; Kulka, Mike; Patel, Isha; Jackson, Scott; Goswami, Biswendu B.
Title: Detection and Identification of Common Food-Borne Viruses with a Tiling Microarray Document date: 2011_5_16
ID: ycs5rtoc_18
Snippet: Microarray hybridization based techniques for the identification of known mutations in viral genomes were initially performed by synthesizing a limited number of probes based on the sequence of wild-type viral and mutated genomes. The probes (individually synthesized) were immobilized on solid supports by hand spotting, and later by automated programmable applicators that could handle several hundred probes [8, 9, 23, 24] These approaches have be.....
Document: Microarray hybridization based techniques for the identification of known mutations in viral genomes were initially performed by synthesizing a limited number of probes based on the sequence of wild-type viral and mutated genomes. The probes (individually synthesized) were immobilized on solid supports by hand spotting, and later by automated programmable applicators that could handle several hundred probes [8, 9, 23, 24] These approaches have been superseded by the newer photolithographic techniques.
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