Title: Development of graft-vs.-host disease-like syndrome in cyclosporine- treated rats after syngeneic bone marrow transplantation. I. Development of cytotoxic T lymphocytes with apparent polyclonal anti-Ia specificity, including autoreactivity Document date: 1985_4_1
ID: rqggh4y2_15
Snippet: Initial studies were undertaken to determine whether rats wtih the syngeneic GVHD syndrome had cytotoxic T lymphocyte activity against self (Lewis) and/ or other rat strains (ACI, BN) not sharing major histocompatibility complex antigens with the Lewis strain of rat. The animals were tested at various intervals after cessation of CsA therapy, and biopsies were taken for histological assessment.....
Document: Initial studies were undertaken to determine whether rats wtih the syngeneic GVHD syndrome had cytotoxic T lymphocyte activity against self (Lewis) and/ or other rat strains (ACI, BN) not sharing major histocompatibility complex antigens with the Lewis strain of rat. The animals were tested at various intervals after cessation of CsA therapy, and biopsies were taken for histological assessment
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