Author: Gadsby, Naomi J.; Russell, Clark D.; McHugh, Martin P.; Mark, Harriet; Conway Morris, Andrew; Laurenson, Ian F.; Hill, Adam T.; Templeton, Kate E.
Title: Comprehensive Molecular Testing for Respiratory Pathogens in Community-Acquired Pneumonia Document date: 2016_4_1
ID: s04e6po9_25
Snippet: Of 316 patients with information available on antimicrobial administration prior to sampling, 268 (84.8%) had received antimicrobials either while in the hospital or in the community during the 72 hours before an LRT specimen was obtained. Prior antimicrobial administration was significantly associated with a patient having a culture-negative LRT specimen (P < .0001; OR = 9.1; 95% CI, 4.1-22.4). Of the 268 patients who had received prior antimicr.....
Document: Of 316 patients with information available on antimicrobial administration prior to sampling, 268 (84.8%) had received antimicrobials either while in the hospital or in the community during the 72 hours before an LRT specimen was obtained. Prior antimicrobial administration was significantly associated with a patient having a culture-negative LRT specimen (P < .0001; OR = 9.1; 95% CI, 4.1-22.4). Of the 268 patients who had received prior antimicrobials, 77.6% (n = 208) had a bacterial pathogen detected by PCR, but only 32.1% (n = 86) were culture positive (P < .0001). The mean combined load of all detected bacteria per patient was significantly higher in patients who had not received antimicrobials prior to sampling (5.40 × 10 9 CFU/mL) compared with those who had received antimicrobials (2.67 × 10 8 CFU/mL; P = .0001).
Search related documents:
Co phrase search for related documents- antimicrobial administration and prior antimicrobial administration: 1, 2
- bacterial pathogen and detect bacteria: 1
- bacterial pathogen and PCR detect: 1, 2
- detect bacteria and PCR detect: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- PCR detect and prior antimicrobial: 1
Co phrase search for related documents, hyperlinks ordered by date