Selected article for: "femoral head and mesenchymal stem cell"
Author: Liu, Li-Hua; Zhang, Qing-Yu; Sun, Wei; Li, Zi-Rong; Gao, Fu-Qiang
Title: Corticosteroid-induced Osteonecrosis of the Femoral Head: Detection, Diagnosis, and Treatment in Earlier Stages
  • Document date: 2017_11_5
    • ID: vvjcxor9_36
    Snippet: The use of autologous concentrated mesenchymal stem cell (MSC) grafting with CD in patients with ONFH showed better outcomes, and the best indication for this procedure is symptomatic ONFH without collapse. A comparative study showed that failed regenerative treatment strategies occurred in the corticosteroid-induced ONFH cases treated with autologous MSC infusion, which collapsed with the decreased ability to differentiate. [51] Bone morphogenet.....
    Document: The use of autologous concentrated mesenchymal stem cell (MSC) grafting with CD in patients with ONFH showed better outcomes, and the best indication for this procedure is symptomatic ONFH without collapse. A comparative study showed that failed regenerative treatment strategies occurred in the corticosteroid-induced ONFH cases treated with autologous MSC infusion, which collapsed with the decreased ability to differentiate. [51] Bone morphogenetic proteins (BMPs) are the key proteins regulating bone re-modeling and healing. The expression levels of BMP gene were analyzed in the normal and necrotic sites of the femoral head. [52] The combination with BMP-7 and/or BMP-2 for the treatment may present more effective means to preserve the femoral head.

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