Selected article for: "rapidly Wuhan spread and Wuhan spread"
Author: Yang Xu; Yi-rong Li; Qiang Zeng; Zhi-bing Lu; Yong-zhe Li; Wei Wu; Sheng-yong Dong; Gang Huang; Xing-huan Wang
Title: Clinical Characteristics of SARS-CoV-2 Pneumonia Compared to Controls in Chinese Han Population
  • Document date: 2020_3_10
    • ID: glq0lckz_38
    Snippet: It has been reported that SARS-CoV directly infects monocytes, macrophages and T lymphocytes in human. 17 The PLD may also be secondary to activation of T lymphocytes. 18 COVID-19 has spread rapidly since it was first identified in Wuhan and has been shown to have a wide spectrum of severity as SARS-CoV-2 binds to ACE2 receptors in 10-20 fold higher affinity than SARS-CoV binds to the same receptors. 7, 19 The report shows SARS-CoV-2 cell entry d.....
    Document: It has been reported that SARS-CoV directly infects monocytes, macrophages and T lymphocytes in human. 17 The PLD may also be secondary to activation of T lymphocytes. 18 COVID-19 has spread rapidly since it was first identified in Wuhan and has been shown to have a wide spectrum of severity as SARS-CoV-2 binds to ACE2 receptors in 10-20 fold higher affinity than SARS-CoV binds to the same receptors. 7, 19 The report shows SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2. 8 Therefore, it is necessary to further study whether lymphocytes have ACE2 receptor and TMPRSS2 expression during the developmental stage since the PLD exists. A SARS-CoV-2 RT-PCR assay for lymphocyte subsets in severe or critical cases should be followed up. Our findings also suggest that All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity.

    Search related documents:
    Co phrase search for related documents
    • critical severe case and SARS bind: 1
    • critical severe case and SARS cell: 1, 2, 3
    • critical severe case and SARS cell entry: 1, 2
    • critical severe case and SARS CoV bind: 1
    • developmental stage and high affinity: 1
    • developmental stage and SARS cell: 1
    • developmental stage and SARS cell entry: 1
    • developmental stage and SARS RT PCR assay: 1
    • high affinity and rapidly spread: 1, 2, 3, 4, 5, 6, 7
    • high affinity and SARS bind: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • high affinity and SARS cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • high affinity and SARS cell entry: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
    • high affinity and SARS CoV bind: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • high affinity and SARS CoV bind high affinity: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • lymphocyte subset and rapidly spread: 1
    • lymphocyte subset and SARS cell: 1, 2, 3, 4
    • rapidly spread and SARS bind: 1, 2, 3, 4, 5, 6
    • rapidly spread and SARS cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • rapidly spread and SARS cell entry: 1, 2, 3, 4, 5, 6, 7