Author: Gupta, D.K.; Verma, M.K.; Anand, R.; Khajuria, R.K.
Title: Development of a validated UPLC–qTOF-MS/MS method for determination of bioactive constituent from Glycyrrhiza glabra Document date: 2013_1_11
ID: rw0qwdes_2
Snippet: Furthermore, it has been found to prevent the development of hepatic carcinoma from hepatitis C and has been demonstrated invitro to be an antiviral agent against SARS-associated corona virus [8, 9] . Keeping in view the importance of plants in Ayurvedic and herbal formulations, it was decided to undertake a comparative study of various extraction procedures of this plant and find out an efficient method for the extraction of glycyrrhizin and gly.....
Document: Furthermore, it has been found to prevent the development of hepatic carcinoma from hepatitis C and has been demonstrated invitro to be an antiviral agent against SARS-associated corona virus [8, 9] . Keeping in view the importance of plants in Ayurvedic and herbal formulations, it was decided to undertake a comparative study of various extraction procedures of this plant and find out an efficient method for the extraction of glycyrrhizin and glycyrrhetic acid. Moreover, method development and validation for the determination of glycyrrhizin (Fig. 1 ) and glycyrrhetic acid (Fig. 2) in extract obtained from different extraction procedures by ultra-performance liquid chromatography quadrupole time of flight mass spectrometry (UPLC-qTOF-MS/MS) have not been reported, prior to this investigation.
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