Selected article for: "chronic inflammation and previous study"

Author: ODEWUMI, CAROLINE; LATINWO, LEKAN M.; SINCLAIR, ANDRE; BADISA, VEERA L.D.; ABDULLAH, AHKINYALA; BADISA, RAMESH B.
Title: Effect of cadmium on the expression levels of interleukin-1a and interleukin-10 cytokines in human lung cells
  • Document date: 2015_9_10
  • ID: roy4420g_2
    Snippet: Our previous study investigated cadmium toxicity and the protective effect of different antioxidant or chelating compounds, which reduce the toxic effect of cadmium in liver cells (12) (13) (14) (15) . Inhalation is one of the predominant causes of cadmium exposure in humans and it has been reported to cause chronic inflammation and is responsible for various lung diseases (16) (17) (18) (19) . Cytokines are the predominant mediators of inflammat.....
    Document: Our previous study investigated cadmium toxicity and the protective effect of different antioxidant or chelating compounds, which reduce the toxic effect of cadmium in liver cells (12) (13) (14) (15) . Inhalation is one of the predominant causes of cadmium exposure in humans and it has been reported to cause chronic inflammation and is responsible for various lung diseases (16) (17) (18) (19) . Cytokines are the predominant mediators of inflammation. Interleukin (IL)-1α is an important pro-inflammatory cytokine, which regulates the expression levels of other cytokines and chemokines (20) (21) (22) . Conversely, cells respond to various toxic insults by secreting different anti-inflammatory cytokines, including IL-10, for defense and repair mechanisms (23) .

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