Title: Development of graft-vs.-host disease-like syndrome in cyclosporine- treated rats after syngeneic bone marrow transplantation. I. Development of cytotoxic T lymphocytes with apparent polyclonal anti-Ia specificity, including autoreactivity Document date: 1985_4_1
ID: rqggh4y2_7
Snippet: Cyclosporine. CsA was the generous gift of Sandoz, Ltd., Basel, Switzerland. The powdered CsA was dissolved in 95% ethanol and added to a 4% Tween-20 solution in deionized H~O. Rats were weighed daily and received 1 ml/100 g/d subcutaneously from the day of marrow infusion for 40 consecutive days. The total dose of CsA per day per rat was 15 mg/kg. Control animals received the identical quantities of the drug diluent (ethanol, 4% Tween-20, H20) w.....
Document: Cyclosporine. CsA was the generous gift of Sandoz, Ltd., Basel, Switzerland. The powdered CsA was dissolved in 95% ethanol and added to a 4% Tween-20 solution in deionized H~O. Rats were weighed daily and received 1 ml/100 g/d subcutaneously from the day of marrow infusion for 40 consecutive days. The total dose of CsA per day per rat was 15 mg/kg. Control animals received the identical quantities of the drug diluent (ethanol, 4% Tween-20, H20) without CsA.
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