Author: Lee, Seung Heon; Yang, Dong-Kun; Kim, Ha-Hyun; Cho, In-Soo
Title: Efficacy of inactivated variant porcine epidemic diarrhea virus vaccines in growing pigs Document date: 2018_1_29
ID: w643jf90_26
Snippet: The serum antibody response induced by the experimental vaccines was assessed by I-ELISA and VN. All of the experimental vaccines induced a significant PEDV-specific serum IgG response to PEDV. The mean IgG levels in all vaccine groups, but not the NVC group, increased continuously after the first and second vaccinations. At 14 and 28 dpv, the mean IgG levels in all vaccine groups were significantly higher than those in the NVC group (p<0.01, unp.....
Document: The serum antibody response induced by the experimental vaccines was assessed by I-ELISA and VN. All of the experimental vaccines induced a significant PEDV-specific serum IgG response to PEDV. The mean IgG levels in all vaccine groups, but not the NVC group, increased continuously after the first and second vaccinations. At 14 and 28 dpv, the mean IgG levels in all vaccine groups were significantly higher than those in the NVC group (p<0.01, unpaired Student's t test) (Fig. 3A) . The mean IgG levels were significantly higher in the ISA201and ISA206-adjuvanted vaccine groups than in the IMS1313and IMSgel-adjuvanted vaccine groups at 14 and 28 dpv (p< 0.05, Tukey's post hoc test) (Fig. 3B) , indicating that the ISA201 and ISA206 adjuvants induced the strongest PEDV-specific IgG response in growing pigs.
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