Author: Sperschneider, Jana; Datta, Amitava
Title: DotKnot: pseudoknot prediction using the probability dot plot under a refined energy model Document date: 2010_1_31
ID: q26f8pv4_1
Snippet: RNA is a versatile nucleic acid, which is no longer seen as the passive intermediate between DNA and proteins. Numerous functional RNAs with an astonishing variety have been uncovered in the past decade. For example, non-coding RNAs participate in a wide range of cellular processes, are able to regulate gene expression and can act as catalyst (1, 2) . Macromolecule function is closely connected to its 3D folding and structure prediction from the .....
Document: RNA is a versatile nucleic acid, which is no longer seen as the passive intermediate between DNA and proteins. Numerous functional RNAs with an astonishing variety have been uncovered in the past decade. For example, non-coding RNAs participate in a wide range of cellular processes, are able to regulate gene expression and can act as catalyst (1, 2) . Macromolecule function is closely connected to its 3D folding and structure prediction from the base sequence is thus of great importance. RNA structure formation is understood to be hierarchical and, therefore, secondary structure prediction is the foundation for determining the tertiary folding (3, 4) .
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