Selected article for: "human lung and lung tissue"
Author: ODEWUMI, CAROLINE; LATINWO, LEKAN M.; SINCLAIR, ANDRE; BADISA, VEERA L.D.; ABDULLAH, AHKINYALA; BADISA, RAMESH B.
Title: Effect of cadmium on the expression levels of interleukin-1a and interleukin-10 cytokines in human lung cells
  • Document date: 2015_9_10
    • ID: roy4420g_15
    Snippet: The widespread industrial usage of cadmium presents a health risk directly and indirectly to humans and other living organisms. Industrial waste fumes, burning of fossil fuels and cigarette smoke are the predominant direct sources of cadmium exposure to humans. It is estimated that 90% of the inhaled cadmium particles are absorbed by lung tissue and cause pulmonary damage, emphysema and lung cancer (16) (17) (18) (19) . Organisms respond to xeno-.....
    Document: The widespread industrial usage of cadmium presents a health risk directly and indirectly to humans and other living organisms. Industrial waste fumes, burning of fossil fuels and cigarette smoke are the predominant direct sources of cadmium exposure to humans. It is estimated that 90% of the inhaled cadmium particles are absorbed by lung tissue and cause pulmonary damage, emphysema and lung cancer (16) (17) (18) (19) . Organisms respond to xeno-biotics via inflammation and it is initiated through various signaling molecules, including cytokines, in the cells. To date, few investigations into the expression levels of the cytokines, IL-1α (pro-inflammatory) and IL-10 (anti-inflammatory), have been reported (27) . Therefore, elucidating the expression levels of IL-1α and IL-10, and the cell viability at various CdCl 2 concentrations and incubation durations in human MRC-9 normal lung and A549 lung cancer cells may provide an understanding of how lung cells response to cadmium toxicity.

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