Selected article for: "acute respiratory and adaptive innate"
Author: Ping Xu; Guo-Dong Sun; Zhi-Zhong Li
Title: Clinical Characteristics of Two Human to Human Transmitted Coronaviruses: Corona Virus Disease 2019 versus Middle East Respiratory Syndrome Coronavirus.
  • Document date: 2020_3_10
    • ID: 2u6ki9dv_35
    Snippet: Coronavirus is an important pathogen causing respiratory and intestinal infection. Of seven identified coronaviruses, the two very pathogenic viruses, SARS-COV and MERS-COV, cause severe ARDS and even acute respiratory failure. With a mortality rate of more than 10% and more than 35% respectively [43] [44] . The four other human coronaviruses In addition, we found that the number of males is more than that of females in either COVID-19 or MERS-CO.....
    Document: Coronavirus is an important pathogen causing respiratory and intestinal infection. Of seven identified coronaviruses, the two very pathogenic viruses, SARS-COV and MERS-COV, cause severe ARDS and even acute respiratory failure. With a mortality rate of more than 10% and more than 35% respectively [43] [44] . The four other human coronaviruses In addition, we found that the number of males is more than that of females in either COVID-19 or MERS-COV population. The possible reason of reduced susceptibility of females to viral infection is that females have a lot of X chromosome and estrogen that are vital components in development of innate and adaptive immunity [47] . Meanwhile, numbers of patients with COVID-19 infection had chronic comorbidities, mainly hypertension, diabetes and cardiovascular disease, which is similar to MERS-COV population. Those results indicate that older adult males with chronic underlying disease might be more susceptibility to COVID-19 or MERS-COV.

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