Author: Shu, Ting; Gan, Tianyu; Bai, Peng; Wang, Xiaotong; Qian, Qi; Zhou, Hui; Cheng, Qi; Qiu, Yang; Yin, Lei; Zhong, Jin; Zhou, Xi
Title: Ebola virus VP35 has novel NTPase and helicase-like activities Document date: 2019_6_20
ID: u3pxycqh_62
Snippet: Moreover, our work shows that GuHCl, an FDA-approved small molecule drug, is able to inhibit the NTPase/helicaselike activities of VP35 in vitro, and more importantly, the replication and transcription of a stable EBOV minigenome replicon in cultured human cells......
Document: Moreover, our work shows that GuHCl, an FDA-approved small molecule drug, is able to inhibit the NTPase/helicaselike activities of VP35 in vitro, and more importantly, the replication and transcription of a stable EBOV minigenome replicon in cultured human cells.
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