Author: Ying Huang; Rui Yang; Ying Xu; Ping Gong
Title: Clinical characteristics of 36 non-survivors with COVID-19 in Wuhan, China Document date: 2020_2_29
ID: 9hh17k86_42
Snippet: Besides, there were 4 (11.11%) non-survivors who had smoking history and 4 (11.11%) had preexisting COPD. According to previous studies on middle east respiratory syndrome coronavirus (MERS-CoV), smokers and COPD patients might be susceptible to MERS. Further, compared to non-smokers, smokers and COPD patients had a higher dipeptidyl peptidase IV (DPP4) expression, which was inversely correlated with lung function and diffusing capacity parameter.....
Document: Besides, there were 4 (11.11%) non-survivors who had smoking history and 4 (11.11%) had preexisting COPD. According to previous studies on middle east respiratory syndrome coronavirus (MERS-CoV), smokers and COPD patients might be susceptible to MERS. Further, compared to non-smokers, smokers and COPD patients had a higher dipeptidyl peptidase IV (DPP4) expression, which was inversely correlated with lung function and diffusing capacity parameters 16 . Although the relationship between smoking history and susceptibility as well as worse outcomes in COVID-19 remains unclear, we cautioned that the prognosis of COVID-19 in patients with smoking history might be more severe.
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