Selected article for: "antiviral treatment and membrane oxygenation"
Author: Jin, Xi; Lian, Jiang-Shan; Hu, Jian-Hua; Gao, Jianguo; Zheng, Lin; Zhang, Yi-Min; Hao, Shao-Rui; Jia, Hong-Yu; Cai, Huan; Zhang, Xiao-Li; Yu, Guo-Dong; Xu, Kai-Jin; Wang, Xiao-Yan; Gu, Jue-Qing; Zhang, Shan-Yan; Ye, Chan-Yuan; Jin, Ci-Liang; Lu, Ying-Feng; Yu, Xia; Yu, Xiao-Peng; Huang, Jian-Rong; Xu, Kang-Li; Ni, Qin; Yu, Cheng-Bo; Zhu, Biao; Li, Yong-Tao; Liu, Jun; Zhao, Hong; Zhang, Xuan; Yu, Liang; Guo, Yong-Zheng; Su, Jun-Wei; Tao, Jing-Jing; Lang, Guan-Jing; Wu, Xiao-Xin; Wu, Wen-Rui; Qv, Ting-Ting; Xiang, Dai-Rong; Yi, Ping; Shi, Ding; Chen, Yanfei; Ren, Yue; Qiu, Yun-Qing; Li, Lan-Juan; Sheng, Jifang; Yang, Yida
Title: Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms
  • Document date: 2020_3_24
    • ID: zph6r4il_25
    Snippet: As shown in table 3, 5 (6.76%), 13 (17.57%) and 1 (1.35%) patient with COVID-19 with GI symptoms had complications of ARDS, liver injury and shock, respectively, where the former two were significantly higher than their counterparts of 2.08% and 8.84% in patients with COVID-19 without GI symptoms, respectively (p=0.034; p=0.035). All 74 patients with COVID-19 with GI symptoms were treated in isolation with supportive and empiric medication, while.....
    Document: As shown in table 3, 5 (6.76%), 13 (17.57%) and 1 (1.35%) patient with COVID-19 with GI symptoms had complications of ARDS, liver injury and shock, respectively, where the former two were significantly higher than their counterparts of 2.08% and 8.84% in patients with COVID-19 without GI symptoms, respectively (p=0.034; p=0.035). All 74 patients with COVID-19 with GI symptoms were treated in isolation with supportive and empiric medication, while 66 (89.19%) patients received antiviral treatment, including interferon-α sprays, arbidol hydrochloride capsules (two tablets three times daily), lopinavir and ritonavir two tablets (500 mg) twice daily, via the oral route. Furthermore, the average time from illness onset to antiviral therapy was 5.56±4.09 days. Compared with Wuhan data, we had lower rates of glucocorticoid and antibiotic use, 14.86% and 41.89%, respectively. No patients received continuous blood purification due to renal failure, and no patients were treated with extracorporeal membrane oxygenation. Until now, only one patient has died. Five (6.76%) patients with COVID-19 with GI symptoms were treated with mechanical ventilation and transferred to the ICU, which was a significantly higher rate than that of 2.08% in the patients with COVID-19 without GI symptoms (p=0.034).

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