Selected article for: "second relapse and severe disease"
Author: Pedersen, Niels C; Perron, Michel; Bannasch, Michael; Montgomery, Elizabeth; Murakami, Eisuke; Liepnieks, Molly; Liu, Hongwei
Title: Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis
  • Document date: 2019_2_13
    • ID: tkw258dc_22
    Snippet: Eighteen of 26 cats that completed at least 12 weeks of uninterrupted primary treatment required no further treatment. However, eight other cats suffered disease relapses within 3-84 days (average 23 days) ( Figure 1 ). This group included the three cats that had temporary breaks in their initial treatment (CT53, CT71, CT80) and five cats (CT53, CT57, CT60, CT68, CT73) that had required extended primary treatment ( Figure 1 ). Disease relapses in.....
    Document: Eighteen of 26 cats that completed at least 12 weeks of uninterrupted primary treatment required no further treatment. However, eight other cats suffered disease relapses within 3-84 days (average 23 days) ( Figure 1 ). This group included the three cats that had temporary breaks in their initial treatment (CT53, CT71, CT80) and five cats (CT53, CT57, CT60, CT68, CT73) that had required extended primary treatment ( Figure 1 ). Disease relapses in 2/8 cats (CT57, CT71) were clearly of a neurological nature with high fever and severe posterior ataxia and incoordination, while disease relapses in the remaining six cats consisted mainly of fever, anorexia and lack of activity. Only one cat (CT60) had an obvious abdominal effusion upon relapse. One cat (CT57) was euthanized 2 weeks after suffering a relapse with neurological signs that failed to respond to a second round of treatment.

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