Selected article for: "efficacious vaccine and vaccine development"

Author: Lee, Seung Heon; Yang, Dong-Kun; Kim, Ha-Hyun; Cho, In-Soo
Title: Efficacy of inactivated variant porcine epidemic diarrhea virus vaccines in growing pigs
  • Document date: 2018_1_29
  • ID: w643jf90_29
    Snippet: Recent outbreaks and global re-emergences of PED pose a substantial threat to the swine industry in Asia and the United States. Indeed, the efficacies of the commercially available inactivated PEDV vaccines based on the SM98, DR-13, and CV-777 strains used in Asian swine-producing countries are uncertain [20] . Most PEDV strains associated with recent severe PED outbreaks were of the G2b genogroup and are; thus, they are antigenically and genetic.....
    Document: Recent outbreaks and global re-emergences of PED pose a substantial threat to the swine industry in Asia and the United States. Indeed, the efficacies of the commercially available inactivated PEDV vaccines based on the SM98, DR-13, and CV-777 strains used in Asian swine-producing countries are uncertain [20] . Most PEDV strains associated with recent severe PED outbreaks were of the G2b genogroup and are; thus, they are antigenically and genetically distinct from the PEDV vaccine strains [14] . This may explain the low protective efficacy of PEDV vaccines against outbreak strains, and suggests that development of an efficacious vaccine is urgently required.

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