Author: Gröner, Albrecht; Broumis, Connie; Fang, Randel; Nowak, Thomas; Popp, Birgit; Schäfer, Wolfram; Roth, Nathan J.
Title: Effective inactivation of a wide range of viruses by pasteurization Document date: 2017_11_16
ID: w19hl2vs_20
Snippet: HIV was inactivated to levels below LOD within 4 hours with RFs of at least 5 log. An exception is the C1 inhibitor concentrate (C1-INH) intermediate with residual infectivity observed after 4 hours and a RF of at least 6.6 log after 8 hours; the fastest inactivation kinetic for HIV was observed for the product intermediate F IX/FX with RFs of at least 9.8 log within 1 hour. BVDV was inactivated to levels below LOD latest within 6 hours with RFs .....
Document: HIV was inactivated to levels below LOD within 4 hours with RFs of at least 5 log. An exception is the C1 inhibitor concentrate (C1-INH) intermediate with residual infectivity observed after 4 hours and a RF of at least 6.6 log after 8 hours; the fastest inactivation kinetic for HIV was observed for the product intermediate F IX/FX with RFs of at least 9.8 log within 1 hour. BVDV was inactivated to levels below LOD latest within 6 hours with RFs of at least 6 log. The inactivation kinetic is comparable for all product intermediates.
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