Selected article for: "compare genome and genome compare"

Author: Aurrecoechea, Cristina; Barreto, Ana; Basenko, Evelina Y.; Brestelli, John; Brunk, Brian P.; Cade, Shon; Crouch, Kathryn; Doherty, Ryan; Falke, Dave; Fischer, Steve; Gajria, Bindu; Harb, Omar S.; Heiges, Mark; Hertz-Fowler, Christiane; Hu, Sufen; Iodice, John; Kissinger, Jessica C.; Lawrence, Cris; Li, Wei; Pinney, Deborah F.; Pulman, Jane A.; Roos, David S.; Shanmugasundram, Achchuthan; Silva-Franco, Fatima; Steinbiss, Sascha; Stoeckert, Christian J.; Spruill, Drew; Wang, Haiming; Warrenfeltz, Susanne; Zheng, Jie
Title: EuPathDB: the eukaryotic pathogen genomics database resource
  • Document date: 2017_1_4
  • ID: t94aufs3_21
    Snippet: Copy number variation. Whole genome resequencing data are used to estimate chromosome and gene copy number in re-sequenced strains (27) . The median read depth is set to the organism's ploidy and each chromosome's median read depth is normalized to this value. Contigs that are not assigned to chromosomes are excluded from this analysis. Gene copy number is similarly calculated using a normalized read depth for each gene. To compare the number of .....
    Document: Copy number variation. Whole genome resequencing data are used to estimate chromosome and gene copy number in re-sequenced strains (27) . The median read depth is set to the organism's ploidy and each chromosome's median read depth is normalized to this value. Contigs that are not assigned to chromosomes are excluded from this analysis. Gene copy number is similarly calculated using a normalized read depth for each gene. To compare the number of genes in the re-sequenced genome to the reference genome, genes are grouped into clusters that are inferred to have originated by duplication. Searches are categorized under Genetic Variation and either return genes with a certain copy number, or genes with different copy numbers between strains.

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