Selected article for: "previous study and pro inflammatory cytokine"
Author: ODEWUMI, CAROLINE; LATINWO, LEKAN M.; SINCLAIR, ANDRE; BADISA, VEERA L.D.; ABDULLAH, AHKINYALA; BADISA, RAMESH B.
Title: Effect of cadmium on the expression levels of interleukin-1a and interleukin-10 cytokines in human lung cells
  • Document date: 2015_9_10
    • ID: roy4420g_21
    Snippet: Lung cancer cells demonstrated higher expression of the anti-inflammatory cytokine, IL-10, compared with the pro-inflammatory cytokine, IL-1α (Fig. 3) . This was consistent with our previously reported findings (24) and another previous study (35) . IL-10 acts as anti-inflammatory cytokine and is also responsible for cell death. IL-10 cytokine has been demonstrated to decrease the translocation of nuclear factor-κB, which is important in increa.....
    Document: Lung cancer cells demonstrated higher expression of the anti-inflammatory cytokine, IL-10, compared with the pro-inflammatory cytokine, IL-1α (Fig. 3) . This was consistent with our previously reported findings (24) and another previous study (35) . IL-10 acts as anti-inflammatory cytokine and is also responsible for cell death. IL-10 cytokine has been demonstrated to decrease the translocation of nuclear factor-κB, which is important in increasing apoptotic markers, which later leads to apoptotic cell death (31) . Therefore, the higher levels of IL-10 cytokine in the A549 lung cancer cells may be one of the reasons for the higher cytotoxicity caused by CdCl 2 (Fig. 1) .

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