Author: ZHANG, NAICHUN; DENG, JIANNING; WU, FENGYAO; LU, XIANGCHAN; HUANG, LEI; ZHAO, MIN
Title: Expression of arginase I and inducible nitric oxide synthase in the peripheral blood and lymph nodes of HIV-positive patients Document date: 2015_11_23
ID: zvnqiy9p_2
Snippet: The damage caused by HIV infection is gradual and multi-staged, and ends in AIDS (3) . Chronic HIV infection may progressively compromise immune functions. The loss of peripheral CD4 + T lymphocytes due to continuous and severe injury has been a marker of AIDS progression and a major cause of immune dysfunction in HIV/AIDS (4) . However, HIV infection-induced chronic inflammation and the reduction in the number of CD4 + T lymphocytes does not ful.....
Document: The damage caused by HIV infection is gradual and multi-staged, and ends in AIDS (3) . Chronic HIV infection may progressively compromise immune functions. The loss of peripheral CD4 + T lymphocytes due to continuous and severe injury has been a marker of AIDS progression and a major cause of immune dysfunction in HIV/AIDS (4) . However, HIV infection-induced chronic inflammation and the reduction in the number of CD4 + T lymphocytes does not fully explain the immune dysfunction, which occurs in the progression of HIV/AIDS.
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