Author: Oh, Seo-ho; Kim Cho, Young-Saeng; Lee, Ho-Bin; Lee, Sang-Mok; Kim, Whee-Soo; Hong, Liang; Cho, Chong-Su; Choi, Yun-Jaie; Kang, Sang-Kee
Title: Enhancement of antigen-specific humoral immune responses and protein solubility through conjugation of bacterial flagellin, Vibrio vulnificus FlaB, to the N-terminus of porcine epidemic diarrhea virus surface protein antigen S0 Document date: 2019_11_5
ID: q4p77ukw_42
Snippet: Here, we evaluated the adjuvant effect of flagellin by the induction of systemic humoral immune response (Fig. 4) . Though many studies immunized the sow through intramuscular route [38] , induction of the virus-specific IgA at colostrum/milk resulted from mucosal immunization is important factor in terms of lactogenic immunity [39] . Further works using target animals, however, is crucial for the development of this antigen as an effective vacci.....
Document: Here, we evaluated the adjuvant effect of flagellin by the induction of systemic humoral immune response (Fig. 4) . Though many studies immunized the sow through intramuscular route [38] , induction of the virus-specific IgA at colostrum/milk resulted from mucosal immunization is important factor in terms of lactogenic immunity [39] . Further works using target animals, however, is crucial for the development of this antigen as an effective vaccine.
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