Author: Lee, Seung Heon; Yang, Dong-Kun; Kim, Ha-Hyun; Cho, In-Soo
Title: Efficacy of inactivated variant porcine epidemic diarrhea virus vaccines in growing pigs Document date: 2018_1_29
ID: w643jf90_3
Snippet: Since 2010, severe PED epidemics have occurred in many swine-producing countries, causing substantial financial losses to their domestic swine industries [14] . In Korea, severe acute diarrhea outbreaks associated with a high mortality rate (approximately 100%) occurred in neonatal piglets in the beginning of November 2013 [15] . Subsequently, the 2014 PED epidemics affected over 33,600 piglets at 169 pig farms (https: //www.kahis.go.kr/), despit.....
Document: Since 2010, severe PED epidemics have occurred in many swine-producing countries, causing substantial financial losses to their domestic swine industries [14] . In Korea, severe acute diarrhea outbreaks associated with a high mortality rate (approximately 100%) occurred in neonatal piglets in the beginning of November 2013 [15] . Subsequently, the 2014 PED epidemics affected over 33,600 piglets at 169 pig farms (https: //www.kahis.go.kr/), despite implementation of a national PEDV vaccination program to prevent the disease on pig farms. The field isolates responsible for this PEDV epidemic are genetically and antigenically different from the PEDV vaccine strains [14, 16] . Therefore, the recent severe PED epidemics have emphasized the importance of establishing effective disease prevention nationwide, which requires development of next-generation vaccines against PEDV.
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