Author: Jin, Xi; Lian, Jiang-Shan; Hu, Jian-Hua; Gao, Jianguo; Zheng, Lin; Zhang, Yi-Min; Hao, Shao-Rui; Jia, Hong-Yu; Cai, Huan; Zhang, Xiao-Li; Yu, Guo-Dong; Xu, Kai-Jin; Wang, Xiao-Yan; Gu, Jue-Qing; Zhang, Shan-Yan; Ye, Chan-Yuan; Jin, Ci-Liang; Lu, Ying-Feng; Yu, Xia; Yu, Xiao-Peng; Huang, Jian-Rong; Xu, Kang-Li; Ni, Qin; Yu, Cheng-Bo; Zhu, Biao; Li, Yong-Tao; Liu, Jun; Zhao, Hong; Zhang, Xuan; Yu, Liang; Guo, Yong-Zheng; Su, Jun-Wei; Tao, Jing-Jing; Lang, Guan-Jing; Wu, Xiao-Xin; Wu, Wen-Rui; Qv, Ting-Ting; Xiang, Dai-Rong; Yi, Ping; Shi, Ding; Chen, Yanfei; Ren, Yue; Qiu, Yun-Qing; Li, Lan-Juan; Sheng, Jifang; Yang, Yida
Title: Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms Document date: 2020_3_24
ID: zph6r4il_27
Snippet: Of severe/critical patients with COVID-19, 22.97% presented with GI symptoms in this study. When compared with mild and common COVID-19, initial univariate analysis of epidemiological, clinical and laboratory variables identified 11 significantly changed risk factors for severe/critical COVID-19, including increased ORs of age, age ≥50 years, period between illness onset and hospital visit, sputum production, any existing medical condition, mul.....
Document: Of severe/critical patients with COVID-19, 22.97% presented with GI symptoms in this study. When compared with mild and common COVID-19, initial univariate analysis of epidemiological, clinical and laboratory variables identified 11 significantly changed risk factors for severe/critical COVID-19, including increased ORs of age, age ≥50 years, period between illness onset and hospital visit, sputum production, any existing medical condition, multiple lung infection, ALT, lactate dehydrogenase (LDH), glucose and CRP, as well as decreased OR of the infected area (online supplementary table 1 ). Based on these variables, further multivariate analysis using the forward method was performed, and we found that sputum production of patients from infected areas such as Wuhan and increased LDH/glucose levels were the independent risk factors for severe/ critical COVID-19 in patients with GI symptoms (table 4) .
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