Author: Morens, David M.; Fauci, Anthony S.
Title: Emerging Infectious Diseases in 2012: 20 Years after the Institute of Medicine Report Document date: 2012_12_11
ID: u178w3kj_17
Snippet: The "one-health" concept, which emphasizes understanding and studying the unity of human and animal infectious diseases (22) , reflects growing awareness that the majority of human EIDs, probably more than 60 per cent (11) , are of animal origin (zoonotic), a realization that has implications not only for disease surveillance but also for understanding pathogenesis and controlling disease. For example, HIV/AIDS, influenza, Lyme disease, tuberculo.....
Document: The "one-health" concept, which emphasizes understanding and studying the unity of human and animal infectious diseases (22) , reflects growing awareness that the majority of human EIDs, probably more than 60 per cent (11) , are of animal origin (zoonotic), a realization that has implications not only for disease surveillance but also for understanding pathogenesis and controlling disease. For example, HIV/AIDS, influenza, Lyme disease, tuberculosis, measles, plague, smallpox, and possibly even leprosy are directly or primarily of animal origin. Viral host switching, in some cases associated with rapid and complicated microbial comutations (23) , has become an important research topic (23, 24) for both newer EIDs, such as SARS, and reemerging ones, such as influenza. The processes by which animal-adapted microorganisms leave their hosts and adapt to new species, such as humans, are largely unknown and represent an important challenge in the study of EIDs.
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