Author: ZHANG, NAICHUN; DENG, JIANNING; WU, FENGYAO; LU, XIANGCHAN; HUANG, LEI; ZHAO, MIN
Title: Expression of arginase I and inducible nitric oxide synthase in the peripheral blood and lymph nodes of HIV-positive patients Document date: 2015_11_23
ID: zvnqiy9p_28
Snippet: In conclusion, the present study suggested that abnormalities in the expression levels of Arg I and iNOS in peripheral blood and LN T cells may be a contributor to compromised immunity in patients with HIV, which are responsible for the significant elevations in viral load during the AIDS phase and the appearance of opportunistic infections. In addition, the expression levels of Arg I and iNOS in the T cells of peripheral blood and LNs may be as .....
Document: In conclusion, the present study suggested that abnormalities in the expression levels of Arg I and iNOS in peripheral blood and LN T cells may be a contributor to compromised immunity in patients with HIV, which are responsible for the significant elevations in viral load during the AIDS phase and the appearance of opportunistic infections. In addition, the expression levels of Arg I and iNOS in the T cells of peripheral blood and LNs may be as a potential parameter to predict disease progression, as the expression levels of Arg I and iNOS in peripheral blood and LN T cells were found to be correlated with HIV load and CD4 + T cell count.
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